Study of Serum Lipoprotein (a) and Lipid Profile in patients with untreated essential hypertension in North Indian population

Aim: Aim of the study was to find out the serum lipoprotein(a) in healthy and essential hypertensive subjects along with the lipid levels in them to assess that lipoprotein(a) measurement could help in risk stratification in these newly diagnosed essential hypertensive group. Material &Method: Eighty newly diagnosed essential hypertensive patients and seventy healthy subjects were included in the study. Sera were collected from them and lipid levels and serum Lipoprotein(a)were estimated in both groups. Result: It was observed that mean level of total cholesterol, Triglyceride, Very Low Density Lipoprotein-Cholesterol and Low Density LipoproteinCholesterol were significantly elevated in hypertensive subjects as compared to controls. Taking 30 mg/dl as the cut off value of Lp(a),majority of the cases had levels more than 30mg/dl(p<0.001) when compared to controls. Conclusion: This study indicates that significantly elevated serum Lp(a) level can be included along with lipid profile for risk stratification in newly diagnosed essential hypertensive patients.